General Summary

Infectious Diseases Institute Makerere University College of Health Sciences seeks to hire suitable candidates for a Phase 3, Randomized, Observer-blinded Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Multivalent Group B Streptococcus Vaccine in Healthy Pregnant Women and their Infants.

Key Responsibilities

• Active Patient Enrollment: Pre-screen patient medical charts, review electronic health records, and evaluate incoming participants against strict protocol inclusion and exclusion criteria.
• Informed Consent: Conduct high-quality, comprehensive informed consent discussions with potential participants, addressing their questions or hesitations regarding investigational vaccine technologies (e.g., mRNA, viral vectors).
• Comprehensive Clinical Screening: Perform detailed baseline physical examinations, analyze vital signs, review complex medical histories, and interpret laboratory screenings to determine whether participants are fit for vaccination.
• Acute Post-Vaccination Care: Deliver immediate and follow-up medical care for trial participants. Monitor and manage localized reactogenicity (e.g., injection site reactions) and systemic reactions (e.g., fevers, fatigue, immune responses).
• Safety Monitoring & Safety Logs: Accurately evaluate, grade, and document all Adverse Events (AEs). Follow up directly with patients reporting symptoms via trialslates and telehealth check-ins.
• Participant Retention: Build strong, empathetic clinical relationships with trial participants to ensure long-term retention and adherence to schedules, hospital deliveries, and follow-up blood draws.

Academic Qualifications

• MBCHB

Person Specification

• Education: MBCHB with experience in OB/GYN.
• Licensure: Medical License in Uganda
• Certifications: Current Good Clinical Practice and responsible conduct of research certification
• Clinical Experience: Background in OBGYN patient management is highly prioritized.
• Prior experience in clinical research
• Strong interpersonal skills with a demonstrated ability to talk comfortably with patients from diverse background communities.
• Experience utilizing electronic medical records (EMR) or clinical trial data capture software.

 

Back Apply

More Details

Job Code: MOBN001
No of Position: 1
Station: IDI Mulago
Classification: Full-time
Duration: 1 Years
Reports to: STUDY COORDINATOR
Posted Date: 2026-11-05 06:20:42.000
Closing Date: 2026-11-18 17:00:00.000

MEDICAL OFFICER (1)

Infectious Diseases Institute Makerere University College of Health Sciences seeks to hire suitable candidates for a Phase 3, Randomized, Observer-blinded Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Multivalent Group B Streptococcus Vaccine in Healthy Pregnant Women and their Infants.

STUDY COORDINATOR (1)

We are seeking a highly organized, detail-oriented Study Coordinator to join our clinical trials site team. In this role, you will manage the daily operations of an upcoming phase III clinical trial for an investigational vaccine. You will serve as the primary operational link between study participants, the Principal Investigator (PI), the study team, and the sponsor. The ideal candidate has strong clinical trial experience, a thorough understanding of Good Clinical Practice (GCP), and a solid baseline background in managing complex handling protocols for biological or temperature-sensitive assets.

RESEARCH MIDWIFE (2)

We are seeking detail-oriented Research Midwives to join our site team. In this role, you will be the primary point of clinical contact for participants, guiding them through the entire journey from their initial inquiry to their final follow-up appointment.

MASTERS STUDENT (5)

1. About O.R. TAMBO AFRICA RESEARCH CHAIR INITIATIVE 

The Strengthening Neuro-Infectious Disease Research Capacity at Makerere University through Tiered Mentorship and Institutional Collaboration project funded through the O.R. TAMBO AFRICA RESEARCH CHAIR INITIATIVE (ORTARCHI) at the Infectious Diseases Institute (IDI), Makerere University, invites applications for fully-funded training scholarships in infectious and neurological diseases research for academic year 2026/2027.

2. Program Overview

This training program is a collaborative between Makerere University, Mbarara University of Science & Technology (MUST), University of Minnesota (USA) and Centre for the AIDS Programme of Research in South Africa (CAPRISA). The program provides multidisciplinary research training in Immunology, Epidemiology, Biostatistics, Pharmacology and Quality Improvement. Trainees will conduct research using existing neuro-infectious disease platforms or other related areas, under expert mentorship. Additionally, the program aims to establish an Infectious Disease Fellowship within the Department of Medicine at Makerere University. This will contribute to building a local and regional workforce of infectious disease specialists.

3. Background

Infectious and neglected tropical diseases remain a leading cause of death in Africa. Neuro-infections such as meningitis, encephalitis, and meningoencephalitis account for a large portion of neurological disease burden especially among immunocompromised individuals, including those living with HIV/AIDS.

In Sub-Saharan Africa:

• Cryptococcal meningitis causes 15–19% of AIDS-related deaths.
• TB meningitis is the deadliest form of TB.
• CNS infections account for 12% of medical admissions in Uganda's national referral hospital, yet most etiologies remain undiagnosed.

Despite the magnitude of this problem, neuro-infections remain under-researched and under-diagnosed, leading to delayed treatment and preventable deaths.

4. Program Goal

The program aims to train and retain a new generation of African physician-scientists who will contribute to human and institutional capacity development in prevention, treatment, and research of infectious diseases. It targets highly motivated individuals committed to advancing careers in infectious diseases, with a specific focus on infectious and neurological diseases.

5. Position: MMed Scholar (5 vacancies at MakCHS and MUST)

• 1 Position MMed Paediatrics at MakCHS
• 2 Positions at MMed Internal Medicine at MakCHS
• 2 Positions at MMed Internal at Mbarara University (MUST)

Eligibility:

• Currently enrolled in second year of the MMed Internal Medicine or Paediatrics programs at Makerere or MMed Internal Medicine at MUST
• Commitment to completing the program full-time

PHD SCHOLAR (1)

1. About O.R. TAMBO AFRICA RESEARCH CHAIR INITIATIVE 

The Strengthening Neuro-Infectious Disease Research Capacity at Makerere University through Tiered Mentorship and Institutional Collaboration project funded through the O.R. TAMBO AFRICA RESEARCH CHAIR INITIATIVE (ORTARCHI) at the Infectious Diseases Institute (IDI), Makerere University, invites applications for fully-funded training scholarships in infectious and neurological diseases research for academic year 2026/2027

2. Program Overview

This training program is a collaborative between Makerere University, Mbarara University of Science & Technology (MUST), University of Minnesota (USA) and Centre for the AIDS Programme of Research in South Africa (CAPRISA). The program provides multidisciplinary research training in Immunology, Epidemiology, Biostatistics, Pharmacology and Quality Improvement. Trainees will conduct research using existing neuro-infectious disease platforms or other related areas, under expert mentorship. Additionally, the program aims to establish an Infectious Disease Fellowship within the Department of Medicine at Makerere University. This will contribute to building a local and regional workforce of infectious disease specialists.

3. Background

Infectious and neglected tropical diseases remain a leading cause of death in Africa. Neuro-infections such as meningitis, encephalitis, and meningoencephalitis account for a large portion of neurological disease burden especially among immunocompromised individuals, including those living with HIV/AIDS.

In Sub-Saharan Africa:

• Cryptococcal meningitis causes 15–19% of AIDS-related deaths.
• TB meningitis is the deadliest form of TB.
• CNS infections account for 12% of medical admissions in Uganda's national referral hospital, yet most etiologies remain undiagnosed.

Despite the magnitude of this problem, neuro-infections remain under-researched and under-diagnosed, leading to delayed treatment and preventable deaths.

4. Program Goal

The program aims to train and retain a new generation of African physician-scientists who will contribute to human and institutional capacity development in prevention, treatment, and research of infectious diseases. It targets highly motivated individuals committed to advancing careers in infectious diseases, with a specific focus on infectious and neurological diseases.

5. Position: PhD Fellowship at Makerere University (1 Position – Department of Internal Medicine – MakCHS)

Eligibility:

• Completed MMed program
• Commitment to fellowship training over 1-2 years.

RESEARCH FELLOW (1)

1. About O.R. TAMBO AFRICA RESEARCH CHAIR INITIATIVE 

The Strengthening Neuro-Infectious Disease Research Capacity at Makerere University through Tiered Mentorship and Institutional Collaboration project funded through the O.R. TAMBO AFRICA RESEARCH CHAIR INITIATIVE (ORTARCHI) at the Infectious Diseases Institute (IDI), Makerere University, invites applications for fully-funded training scholarships in infectious and neurological diseases research for academic year 2026/2027

2. Program Overview

This training program is a collaborative between Makerere University, Mbarara University of Science & Technology (MUST), University of Minnesota (USA) and Centre for the AIDS Programme of Research in South Africa (CAPRISA). The program provides multidisciplinary research training in Immunology, Epidemiology, Biostatistics, Pharmacology and Quality Improvement. Trainees will conduct research using existing neuro-infectious disease platforms or other related areas, under expert mentorship. Additionally, the program aims to establish an Infectious Disease Fellowship within the Department of Medicine at Makerere University. This will contribute to building a local and regional workforce of infectious disease specialists.

3. Background

Infectious and neglected tropical diseases remain a leading cause of death in Africa. Neuro-infections such as meningitis, encephalitis, and meningoencephalitis account for a large portion of neurological disease burden especially among immunocompromised individuals, including those living with HIV/AIDS.

In Sub-Saharan Africa:

• Cryptococcal meningitis causes 15–19% of AIDS-related deaths.
• TB meningitis is the deadliest form of TB.
• CNS infections account for 12% of medical admissions in Uganda's national referral hospital, yet most etiologies remain undiagnosed.

Despite the magnitude of this problem, neuro-infections remain under-researched and under-diagnosed, leading to delayed treatment and preventable deaths.

4. Program Goal

The program aims to train and retain a new generation of African physician-scientists who will contribute to human and institutional capacity development in prevention, treatment, and research of infectious diseases. It targets highly motivated individuals committed to advancing careers in infectious diseases, with a specific focus on infectious and neurological diseases.

5. Position: Post-MMed Fellowship, MakCHS (1 Vacancy)

Eligibility:

• Completed MMed program
• Commitment to fellowship training over 1-2 years.