Uganda has experienced several outbreaks caused by filoviruses (Ebola and Marburg viruses). IDI is part of the JMEDICC consortium working in collaboration with Makerere University Walter Reed Project and United States Department of Defence partners. JMEDICC is establishing a pilot demonstration of clinical research capabilities to improve sepsis patient management and to build capacity to conduct therapeutic research in a filovirus outbreak setting. In the initial phase, an observational sepsis study is being conducted at Fort Portal Regional Referral Hospital with IDI supporting clinical management, infection prevention and control and laboratory microbiology aspects.