The value and benefits of research depend on the integrity of research. While there can be national and disciplinary differences in the way research is organized and conducted, there are also principles and professional responsibilities that are fundamental to the integrity of research wherever it is conducted. Responsible Conduct of Research is essential to society’s trust in the scientific enterprise. Principles of Research Integrity provide a foundation for good research practices and professional responsibilities. Although the principles are not legally binding, they provide global guidance to researchers and research institutions. National and regional regulatory agencies, such as UNCST and NDA, issue legally binding policies and regulations for research integrity. At IDI, the institute’s Research Ethics Committee reviews research proposals to formally assess if the research is ethical and conforms to recognized ethical standards, which includes respecting the dignity, rights, safety, and well-being of the people who take part.